Custom iPSC Differentiation

Directed differentiation of iPSCs to neural cells, cardiomyocytes and other cell types

High purity, cost effective, quick turnaround, technical support

We provide cost-effective services to generate multiple cell types from your iPS cell lines. Our Standard Operating Procedures (SOPs) are tailored for large scale production of a number of neural and cardiovascular cell types within a short period of time. We apply fully defined differentiation culture conditions in order to achieve high differentiation efficiency, high purity and minimal lot-to-lot variation.

The process doesn't stop at the point you receive the cells from us. Our dedicated specialists will share their expertise and provide ongoing support to facilitate adaptation of the cells in your experimental systems. We make sure our products work for you, and we take this seriously! If you encounter any technical issue, we will discuss it with you on the phone or send a specialist to your facility to identify the potential cause and demonstrate the culture procedures first hand. 

  iPSC-derived neural cells

      iPSC-derived cardiomyocytes

      Inquire for other cell types

What we can do for you

Source specific donor samples (e.g. fibroblasts, blood cells and iPS cells)

Directed differentiation of iPS cells to multiple cell types, including cardiomyocytes, endothelial cells and cerebral cortical, dopaminergic and sensory neural cells

Differentiate multiple iPS cell lines at the same time

Characterize the differentiated cells with ICC of lineage-specific markers

Provide optimized culture media and substrates for the cell type of interest

Provide cell pellets in RNAlater® or Allprotect

Provide onsite training on how to adapt the custom-made cells in your application

Reprogram human somatic cells to iPS cells Find out more

Genome editing and creation of isogenic cell lines with CRISPR-Cas system Find out more
The turnaround time for directed differentiation is approximately 2 months. At least three frozen vials of iPS cells per sample will be needed. One vial will be thawed and tested for mycoplasma. We will start the differentiation process once the quarantine is completed.

What our customers say...

"I've been able to grow all the cells that Axol generated for me from my patient lines. All the cells provided grew well and I'm very happy with the service as well as the quality of the cells."

 Dr David Millar, Human Molecular Genetics, Cardiff University

"Axol has provided us with more than a fast and reliable supply of functional cortical human iPSC derived neurons. It has also given us access to the collective expertise of Axol, whom we now view as much a collaborator as a company”

 Dr Eric Hill, Clinical and Systems Neuroscience, Aston University

"Axol Bioscience has been a valued and important supplier to our lab’s research since the company was founded. We began working with sample product and were rapidly convinced by the quality of the cells, such that we now have long term orders in place for 2 neural precursor lines. Additionally, we have recommended Axol cells to several of our closest collaborators. The cells supplied to us by Axol represent exceptional value for money, but, most importantly, save us a great deal of valuable research time. Throughout our dealings with the company, service and support have always been excellent.”

 Dr Paul Charlesworth, Physiology, University of Cambridge

Contact us to find out more!