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Currently there are no definitive therapies for CNS (central nervous system) and spinal cord injuries. The aim of a neural organoid is to overcome limitations with current therapies and provide better solutions for a damaged human CNS or a spinal cord injury. A neural organoid might also be useful in conducting a neurotoxicity test for chemical agents.
Axol Human iPSC-Derived Sensory Neurons were cultured on a multiple-electrode array platform (Alpha MED Scientific) in order to investigate the potential of these cells to be used as an in vitro model that can recapitulate the sensation of human pain. This study showed that cultured Axol human iPSC-Derived Sensory Neurons display the typical characteristics and firing responses of human sensory neurons.
Characterization of human iPSC-Derived Microglia using live-cell imaging reveals hallmarks of morphology and function
This study characterized human iPSC-derived microglia (Axol Bioscience) using IncuCyte® Live Cell assays (Essen BioScience, part of the Sartorius Group) to validate their morphological and functional features, offering insights into their suitability for immune and neurodegenerative disease research.