The All-in-One Starter Kit for Human iPSC-derived Sensory Neurons
The addition of the new MATURATION MAXIMIZER supplement to the sensory neuron kit gives:
SIGNIFICANTLY INCREASED KEY MARKER EXPRESSION & ACCELERATE NEURONAL MATURATION
An average increase of 30-45% of neurons expressing TRPv1, Nav1.7 and Nav1.8 in week 4 of culture; 90% neurons response to capsaicin on day 22.
FASTER MATURATION, QUICKER RESULTS
ax0058 MATURATION MAXIMIZER Supplement can only be used with Axol's Human iPSC-derived Sensory Neuron Progenitors (ax0055 or ax0555)
An average increase of 30-45% of neurons expressing TRPv1, Nav1.7 and Nav1.8 in week 4 of culture; 90% neurons response to capsaicin on day 22.
FASTER MATURATION, QUICKER RESULTS
An average increase of 30-45% of neurons expressing TRPv1, Nav1.7 and Nav1.8 in week 4 of culture; 90% neurons response to capsaicin on day 22.
FASTER MATURATION, QUICKER RESULTS
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2x 250 mL Striatal Neuron Basal Medium (Store at 4 oC upon receipt)
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2x 7.5 mL Striatal Neuron Medium Supplement (Store at or below -20 oC upon receipt)
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1 vial of Differentiation Supplement A (Store at 4 oC upon receipt)
Our iPSC-derived astrocytes are cryopreserved for convenience, and they are assay-ready within 48 hrs. Once thawed, Axol's astrocytes display all indicative astrocytic markers and will respond to glutamate stimulation, a key functional characteristic within 48-60 hrs. They also express markers showing that Axol's Human iPSC-derived astrocytes are physiologically representative of human primary astrocytes.
Axol’s Cell Recovery Enzyme is exclusively designed for the digestion of the bio-friendly Axol hydrogel enabling recovery of cells, spheroids, organoids or tissue samples intact.
Axol's biocompatible hydrogel is supplied ready to use in a syringe and mimics the extracellular matrix, supporting cell growth and differentiation with consistent results. Tested applications range from: 3D cell culture and organ-on-a-chip models, through to drug release studies and 3D printing.
FUNCTIONAL MATURITY IN LESS THAN 21 DAYS
The maturation accelerator supplement is specially designed to recreate the developmental milieu of motor neurons, driving rapid maturation. Culturing our iPSC-derived motor neuron progenitor cells in this supplemented media provides functionally mature neurons in 14 days that are assay ready by day 21. This is down from 8 weeks!
FASTER MATURATION, QUICKER RESULTS
Please be sure to include the following reagents with your order.
ax0044 - Unlock - fully defined & gentle detachment buffer 25 mL
ax139800 - Recombinant Human Brain-derived Neurotrophic Factor (BDNF)
ax139855 - Human GDNF
ax139888 - Recombinant Human Ciliary - Neurotrophic Factor (CNTF)
Sensory Neuron Maintenance Medium for the maintenance of sensory neuron progenitors and derived neurons.
Axol' Fibroblast Plating & Growth Medium has been optimized to maximise the recovery and viability of our cryopreserved human fibroblasts upon revival.