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Amyloid Precursor Protein (APP) (NT)

Accumulation of the amyloid- peptide (A ) in the cerebral cortex is a critical event in the pathogenesis of AlzheimerÕs disease. The amyloid protein precursor (APP) is cleaved by secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for secretase to generate the 4 kDa amyloid- peptide (A ), which is deposited in the brains of all suffers of AlzheimerÕs disease.

Product Code: ax1080069 (100 µg) Categories: .

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Product Specification

Application Western Blot
Host Rabbit
Size 100 µg
Species reactivity Human|Mouse|Rat
Isotype IgG
Shipping conditions Ambient temperature
Storage conditions -20°C