Accumulation of the amyloid- peptide (A ) in the cerebral cortex is a critical event in the pathogenesis of AlzheimerÕs disease. The amyloid protein precursor (APP) is cleaved by secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for secretase to generate the 4 kDa amyloid- peptide (A ), which is deposited in the brains of all suffers of AlzheimerÕs disease.
We accept Visa and MasterCard in our online store.
We can get your purchases to you wherever you are.
As an Axol customer you have access to our support team and product specialists.