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Animal-Free Human PDGF-AB

Platelet Derived Growth Factor-AB

Product Code: ax5960021 (500 µg) Categories: .

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Features & Benefits

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

Product Specification

Solubility Lyophilized from a sterile (0.2 micron) filtered aqueous solution
Size 500 ug
Purity ≥95
Shipping conditions Ambient temperature
Storage conditions Room temperature
Source E.coli
Reconstitution Sterile water at 0.1 mg/mL