Assay-Ready Expanded (ARE) Hepatocytes, Genotoxicity Assay Validated

520.00

Assay-Ready Expanded (ARE) Hepatocytes, Genotoxicity Assay Validated (1 million cells)

Product Code: ax3703 Categories: .

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Axol Assay-Ready Expanded (ARE) Hepatocytes are primary human hepatocytes that have been expanded in vitro so large batch sizes (up to 2000 vials) are available, ensuring a reliable and consistent source of primary hepatocytes. They are ready-to-use and should be used directly for downstream applications. ARE Hepatocytes express CYP enzymes, are metabolically functional, are polarized and can be infected by the Hepatitis C virus. Our Genotoxicity Validated ARE Hepatocytes have been functionally validated for micronucleus genotoxicity assays when used in conjunction with ARE Hepatocyte Genotoxicity Assay Medium.

ARE Hepatocyte Application Data

Metabolism, CYP induction/inhibition, Hepatotoxicity, Genotoxicity and Co-culture data 

See the Application Data

Donor gender Female
Donor age at sampling 6 yrs
Genetic modification Previous activation of the oncostatin M pathway
Size 1 million cells
Growth properties Adherent
Shipping conditions Dry ice
Storage conditions Liquid nitrogen
Xeno free No
Usage notes Please see our protocol for detailed instructions. Our Thawing Medium should be used when thawing ARE Hepatocytes. Our Genotoxicity Assay Medium should be used to perform micronucleus assays. Culture vessels must be coated with Type I Collagen (not provided).
Condition of sale The end user is not permitted to expand or re-freeze the cells
  • Read nowLevy G, Bomze D, Heinz S. Long-term culture and expansion of primary human hepatocytes. Nature Biotechnology (2015)