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BCL11B / CTIP2 Antibody

Purified anti-BCL11B / CTIP2 Antibody

Product Code: ax114659 (100 ug) Categories: .

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Features & Benefits

Axol's anti-BCL11B / CTIP2 antibody is protein G affinity purified.

The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies.

Recommended dilution: IHC:1:20-1:200

Product Specification

Abbreviation B-cell lymphoma/leukemia 11B
UniProt ID Q9C0K0
Host Rabbit
Conjugate Non-conjugated
Purification >95%, Protein G purified
Alias B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUPTF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1), BCL11B, CTIP2 RIT1
Research Area Epigenetics and Nuclear Signaling
Target Names BCL11B
Tested applications ELISA, IHC
Species reactivity Human
Immunogen Recombinant human B-cell lymphoma/leukemia 11B protein (500-550AA)
Storage buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality Polyclonal
Isotype IgG
Storage conditions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.