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BCRP (ATP-binding cassette sub-family G member 2)

BCRP acts as a xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Product Code: ax1080234 (100 µg) Categories: .

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Product Specification

Application Immunohistochemistry (paraffin-embedded)
Host Rabbit
Size 100 µg
Species reactivity Human
Isotype Ig
Shipping conditions Ambient temperature
Storage conditions -20°C