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Calcium Homeostasis Modulator Protein 1

CALHM1 controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration. It controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca2+ dependent manner. However, no association between CALHM1 and AlzheimerÕs risk is unclear. Member of the FAM26 family of proteins. CALHM1 is predominantly expressed in the adult brain. It has also been detected in retinoic acid-differentiated SH-SY5Y cells. Also colocalizes with HSPA5 at the endoplasmic reticulum.

Product Code: ax1080344 (100 µg) Categories: .

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Product Specification

Application Western blotting|ELISA
Host Rabbit
Size 100 µg
Species reactivity Human
Isotype IgG
Shipping conditions Ambient temperature
Storage conditions -20°C