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Identification of CD4 human helper/inducer T cells expressing the 60,000 M.W. surface antigen (HLA class II reactive). CD4 is present in low density on monocytes. CD45RA recognizes Mr. 220-kdalton of the leucocyte antigen (LCA). CD45RA antigen is a member of the CD45 antigen family that also includes CD45, CD45RO, and CD45RB antigens. CD45RA is Expressed on approximately 75% of CD8 lymphocytes and 50% of CD4 lymphocytes, all B cells and NK Cells. CD45RA antigen is expressed on naive T lymphocytes, antigen density decreases upon in vitro activation. A decrease antigen density has been demonstrated for CD4+CD45RA+subset with active multiple sclerosis.

Product Code: ax1081125 (100 tests) Categories: .

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Product Specification

Application Flow cytometry
Host Mouse
Size 100 tests
Species reactivity Human
Isotype IgG1 (F)/IgG1 (PE)
Shipping conditions Ambient temperature
Storage conditions +4°C