Cefotaxime Sodium is the sodium salt form of cefotaxime, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Cefotaxime sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to the second and first generation cephalosporins, cefotaxime sodium is more active against gram-negative bacteria and less active against gram-positive bacteria. CAS Number: 64485-93-4; Synonyms: CEFOTAXIME SODIUM SALT; Sodium cefotaxime; Tolycar; Pretor; Molecular Formula: C16H16N5NaO7S2 Molecular Weight: 477.442 g/mol InChI Key: AZZMGZXNTDTSME-JUZDKLSSSA-M
binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall
Chemical name
Cefotaxime sodium, USP Grade
Molecular weight
477.442
Molecular formula
C16H16N5NaO7S2
Physical description
White, light yellow powder
Solubility
Soluble in water
Size
1 g
Shipping conditions
Ambient temperature
Storage conditions
-20°C
Stability
Store desiccated
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