A non denaturing zwitterionic detergent with characteristics similar to CHAPS, although more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins. CHAPSO has been used in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins. It has also been used in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range. It can be used for solubilization of membrane proteins. Both CHAPS and CHAPSO have low light absorbance in the ultraviolet region of the electromagnetic spectrum, which is useful for monitoring ongoing chemical reactions or protein-protein binding with UV/Vis spectroscopy. CAS Number: 82473-24-3; Synonyms: MFCD00081079; CHAPS Hydroxy analog; BioXtra; AC1L3U2M; 3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulfonate; Molecular Formula: C32H58N2O8S Molecular Weight: 630.882 g/mol (anhydrous basis) InChI Key: GUQQBLRVXOUDTN-XOHPMCGNSA-N
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