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Chromosome Associated Protein-E

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.

Product Code: ax1081510 (100 µg) Categories: .

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Product Specification

Application Western Blot
Host Mouse
Size 100 µg
Species reactivity Human
Clone number E1M
Isotype IgG
Shipping conditions Ambient temperature
Storage conditions -20°C