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Ciglitazone

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PPARg agonist CAS#: 74772-77-3 Citations: 1) Cantello et al. (1994) [[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents J. Med. Chem. 37 3977. / 2) Xin et al. (1999) Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo J. Biol. Chem. 274 9116

Product Code: ax133992 (5 mg)

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Product Specification

Function / pharmacology PPARgamma agonist (EC50=3 µM). Stimulates adipogenesis in human mesenchymal stem cells. Inhibits HUVEC differentiation and angiogenesis. Cell permeable.
Chemical name (±)-5-[4-(1-Methylcyclohexylmethoxy)-benzyl]thiazolidine-2,4-dione
Molecular weight 333.45
Molecular formula C18H23NO3S
Physical description Tan solid
Solubility DMSO (25 mg/ml) Ethanol (25 mg/ml)
Size 5 mg
Stability Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.