Duchenne Muscular Dystrophy (DMD) is a genetic disease resulting in muscular degeneration due to a mutation to the gene that produces Dystrophin. It affects approximately 1 in 3,500 male births. The progressive weakening of muscles can cause severe cardiovascular and respiratory issues that limit life expectency to the mid twenties.
The Fibroblasts provided have been isolated from a patient clinically diagnosed with DMD and can readily be reprogrammed to induced pluripotent stem cells and differentiated into a range of cells types in your laboratory.
If you would prefer this to be taken care of for you by our team at Axol, we offer a Reprogramming and Differentiation service as part of our Custom Projects
All of the cells provided are tested and are negative for HIV-1, HIV-2, Hepatitis B and Hepatitis C as detected by PCR.
The cells are confirmed to be negative for Mycoplasma and other detectable microbial contamination.