• Search


Please enquire for the latest availability and price information.

Dynamin inhibitor CAS#: 304448-55-3 Citations: 1) Macia et al. (2006), Dynasore, a cell-permeable inhibitor of dynamin; Dev. Cell, 10 839 2) Kirschhausen et al. (2008), Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis; Methods Enzymol., 438 77 3) Lu et al. (2009), Dynamin and activity regulate synaptic vesicle recycling in sympathetic neurons; J. Biol. Chem., 284 1930 4) Chung et al. (2010), Acute dynamin inhibition dissects synaptic vesicle recycling pathways that drive spontaneous and evoked neurotransmission; J. Neurosci., 30 1363 5) Poirer et al. (2009), Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route; J. Biol. Chem., 284 28856

Product Code: ax43561 (5 mg)

Payment Options

We accept Visa and MasterCard in our online store.

Worldwide Shipping

We can get your purchases to you wherever you are.

Customer Care

As an Axol customer you have access to our support team and product specialists.

Product Specification

Function / pharmacology Dynasore is a noncompetitive inhibitor of dynamin GTPase activity and blocks dynamin-dependent endocytosis in cells, including neurons. It inhibits the GTPase activity of dynamin1, dynamin2, and Drp1 (mitochondrial dynamin). It is cell permeable, fast acting (seconds) and reversible.1,2 An extremely useful tool for studying endocytosis and other cellular events which are dependent on dynamin.3-5
Chemical name 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
Molecular weight 322.32
Molecular formula C18H14N2O4
Physical description Beige solid
Solubility DMSO (30 mg/ml) Ethanol (1 mg/ml)
Size 5 mg
Stability Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.