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EGFR

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor- (TGF- ), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Product Code: ax1082093 (100 µg) Categories: .

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Product Specification

Application WB of Extracellular domain|Flow Cytometry|IF|IP (native only)|IHC (Paraffin)
Host Mouse
Size 100 µg
Species reactivity Human does not react with mouse and rat. Others not known.
Clone number H11
Isotype IgG1
Shipping conditions Ambient temperature
Storage conditions -20°C