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Estrogen Receptor

The estrogen receptor (ER) gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Product Code: ax1082225 (100 µg) Categories: .

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Product Specification

Application Western Blotting|Immunoprecipitation|Gel Supershift|Binding blocking|Chromatin Precipitation
Host Mouse
Size 100 µg
Species reactivity Human|Mouse|Rat|Sheep|Rabbit|Hamster|Cow|Pig|Dog|Chicken
Clone number TE111.5D11
Isotype IgG1
Shipping conditions Ambient temperature
Storage conditions -20°C