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FBXW7

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.

Product Code: ax1082280 (50 µg) Categories: .

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Product Specification

Application Western Blot
Host Rabbit
Size 50 µg
Species reactivity Human
Shipping conditions Ambient temperature
Storage conditions -20°C