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TFAM (Transcription Factor A, Mitochondrial) binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation, and DNA replication and repair. The protein is required for accurate and efficient promoter recognition by mitochondrial RNA polymerase. Sequence polymorphisms in the TFAM gene are associated with Alzheimer's and Parkinson's diseases. Other diseases associated with TFAM include Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form and Deoxyguanosine Kinase Deficiency.

Product Code: ax33007118 (25 µg) Categories: .

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Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB, IHC-P
Host Mouse
Specificity TFAM
Size 25 µg
Species reactivity Human
Clonality Monoclonal
Clone number 18G102B2E11
Isotype Mouse IgG2b, κ
Shipping conditions Blue ice
Storage conditions -20°C
Formulation This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.