This kit from Axol enables you to derive cerebral cortical neurons from iPSC-derived neural stem / progenitor cells (NSCs) under fully defined neural induction conditions. The NSCs provided in this kit are cryopreserved in our proprietary freezing medium. After thawing and plating, the cells terminally differentiate to acquire mature electrophysiological properties, and form functional synaptic networks over a period of 30 ~ 40 days.
Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer’s disease, autism, epilepsy and stroke. Despite strong interest in these diseases, high quality human in vitro cell models for cortical neurophysiology have been unavailable until now. With Axol neurons and NSCs, we provide neuroscience researchers with a high quality in vitro human system to complement their existing studies of cortical development, function and diseases using animal models.
HLA Class I type: A3 A33, B7(Bw6) B7(Bw6), Cw7 Cw7