Axol iPSC-Derived Mature Astrocyte Kit contains cryopreserved mature astrocytes together with optimized Astrocyte Maintenance Medium to maintain the astrocytes. The astrocytes are derived from an iPSC line from a healthy donor. More than 80% of the cells are GFAP+ (Glial Fibrillary Acidic Protein) and ≤15% of the cells are TUJ1+ (neuronal class III ß-tubulin) neurons.
Comparing marker expression in iPSC-derived
and primary astrocytes using immunocytochemistry
Expression of GFAP, S100, nestin, MAP2, SOX2, ALDH1L1, glutamine synthetase, EAAT1 and integrin beta 5 in our iPSC-derived mature astrocytes, competitor cells and primary astrocytes. (Data provided by Susanne Zach, Boehringer Ingelheim.)