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Description
Axol Human iPSC-Derived Motor Neuron Progenitors are derived from a healthy male donor.
Axol iPSCs were differentiated to motor neuron progenitors using a combination of small molecules to regulate multiple signalling pathways. Initial expansion of iPSC-Motor Neuron Progenitors is possible before the terminal differentiation to motor neurons.
Axol Human iPSC-Derived Motor Neurons have been characterised by ICC and the motor neurons after 14 days in culture express HB9, LIM3, OLIG2 and TUJ1. After a further 14 days they express choline acetyltransferase (ChAT) and islet-1 (ISL1).
Product Specification
Starting material
Fibroblasts
Donor gender
Male
Donor age at sampling
74 yrs
Karyotype
Normal
Reprogramming method
Episomal vector
Induction method
Monolayer & chemically defined medium
Genetic modification
None
Size
≥2 million cells
Kit components
1 vial of Motor Neuron Progenitors (≥2 million cells)
Axol Human iPSC-Derived Motor Neuron Progenitors are derived from a healthy male donor.
Axol iPSCs were differentiated to motor neuron progenitors using a combination of small molecules to regulate multiple signalling pathways. Initial expansion of iPSC-Motor Neuron Progenitors is possible before the terminal differentiation to motor neurons.
Axol Human iPSC-Derived Motor Neurons have been characterised by ICC and the motor neurons after 14 days in culture express HB9, LIM3, OLIG2 and TUJ1. After a further 14 days they express choline acetyltransferase (ChAT) and islet-1 (ISL1).
Starting material
Fibroblasts
Donor gender
Male
Donor age at sampling
74 yrs
Karyotype
Normal
Reprogramming method
Episomal vector
Induction method
Monolayer & chemically defined medium
Genetic modification
None
Size
≥2 million cells
Kit components
1 vial of Motor Neuron Progenitors (≥2 million cells)
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