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Description
Axol Human iPSC-Derived Motor Neuron Progenitors are derived from a healthy male donor.
Axol iPSCs were differentiated to motor neuron progenitors using a combination of small molecules to regulate multiple signalling pathways. Initial expansion of iPSC-Motor Neuron Progenitors is possible before the terminal differentiation to motor neurons.
Axol Human iPSC-Derived Motor Neurons have been characterised by ICC and the motor neurons after 14 days in culture express HB9, LIM3, OLIG2 and TUJ1. After a further 14 days they express choline acetyltransferase (ChAT) and islet-1 (ISL1).
Product Specification
| Starting material | Fibroblasts |
| Donor gender | Male |
| Donor age at sampling | 74 yrs |
| Karyotype | Normal |
| Reprogramming method | Episomal vector |
| Induction method | Monolayer & chemically defined medium |
| Genetic modification | None |
| Size | ≥2 million cells |
| Kit components | 1 vial of Motor Neuron Progenitors (≥2 million cells) |
| Growth properties | Adherent |
| Shipping conditions | Dry ice |
| Storage conditions | Liquid nitrogen |