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Human iPSC-Derived Motor Neuron Progenitors

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Axol Human iPSC-Derived Motor Neuron Progenitors are derived from a healthy male donor. 

Axol iPSCs were differentiated to motor neuron progenitors using a combination of small molecules to regulate multiple signalling pathways. Initial expansion of iPSC-Motor Neuron Progenitors is possible before the terminal differentiation to motor neurons. 

Axol Human iPSC-Derived Motor Neurons have been characterised by ICC and the motor neurons after 14 days in culture express HB9, LIM3, OLIG2 and TUJ1. After a further 14 days they express choline acetyltransferase (ChAT) and islet-1 (ISL1).

Product Specification

Starting material Fibroblasts
Donor gender Male
Donor age at sampling 74 yrs
Karyotype Normal
Reprogramming method Episomal vector
Induction method Monolayer & chemically defined medium
Genetic modification None
Size ≥2 million cells
Kit components 1 vial of Motor Neuron Progenitors (≥2 million cells)
Growth properties Adherent
Shipping conditions Dry ice
Storage conditions Liquid nitrogen

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