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Features & Benefits
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues.
Product Specification
Size
10µg
Purity
Verified by SDS-PAGE and, where possible, by RP-HPLC
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues.
Size
10µg
Purity
Verified by SDS-PAGE and, where possible, by RP-HPLC
Shipping conditions
Ambient temperature
Storage conditions
See CoA shipped with product
Source
E.coli
Endotoxin level
< 0.1 ng/μg of protein (< 1 EU/μg)
Reconstitution
See CoA shipped with product
Stability
See CoA shipped with product
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