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Hypericin

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Protein kinase C inhibitor CAS#: 548-04-9 Citations: 1) Kubin et al., (2005) Hypericin – the facts about a controversial agent; Current Pharm.Des. 11 233 / 2) Theodossiou et al., (2009) The multifaceted photocytotoxic profile of hypericin; Mol.Pharmacol 6 1775

Product Code: ax44782 (1 mg)

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Product Specification

Function / pharmacology Natural product found in St. John’s Wort (Hypericum perforatum). A multifunctional agent that has been reported to be antidepressive, antineoplastic, antitumor and antiviral. Inhibitory effects have been demonstrated on various enzyme including MAO, PKC, dopamine-ß-hydroxylase, reverse transcriptase, telomerase and CYP.1 Hypericin can cause photosensitivity – as a result, it is being investigated as an agent in photodynamic therapy.2
Chemical name 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Molecular weight 504.45
Molecular formula C30H16O8
Physical description Brown solid
Solubility DMSO (25 mg/ml) Ethanol (5 mg/ml)
Size 1 mg
Stability Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.