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Hedgehog pathway CAS#: 469-59-0 Citations: 1) Cooper et al. (1998), Teratogen-mediated inhibition of target tissue response to Shh signaling; Science, 280 1603 2) Mistretta et al. (2003), Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning: fungiform papillae double in number and form in novel locations in dorsal lingual epithelium; Dev. Biol., 254 1 3) Ghezale et al. (2013), Cyclopamine and jervine induce COX-2 overexpression in human erythroleukemia cells but only cyclopamine has a pro-apoptotic effect; Exp. Cell Res., 319 1043
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