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MEK1/2 (Ser218/222)

MEK 1 and MEK 2 are integral components of the MAP kinase cascade that regulates cell growth and differentiation and this pathway also plays a key role in synaptic plasticity in brain. Activation of MEK 1/2 occurs via phosphorylation of two serine residues (Ser218 and Ser222). Activated MEK 1/2 then acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on ERK. This phosphorylation of ERK by MEK 1/2 is a critical step in the MAP kinase cascade.

Product Code: ax1083622 (10 miniblots) Categories: .

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Product Specification

Application Western Blot|Dot Blot
Host Rabbit
Size 10 Miniblots
Species reactivity Human|Mouse|Rat|Xenopus
Isotype IgG
Shipping conditions Blue ice
Storage conditions -20°C