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Minoxidil

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KATP channel opener CAS#: 38304-91-5 Citations: 1) Meisheri et al. (1988), Mechanism of action of minoxidil sulfate-induced vsodialtion: a role for increased K+ permeability. J.Pharmacol.Exp.Ther., 245 7 / 2) Messenger and Rundegren (2004) Minoxidil:mechanisms of action on hair growth. Br.J.Dermatol. 150 186

Product Code: ax42285 (100 mg)

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Product Specification

Function / pharmacology Minoxidil is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle.1 Active metabolite is Minoxidil sulfate (IC50 = 0.14 µM). Mainly used as a treatment for alopecia because of its observed hair regrowth ability.2
Chemical name 6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide
Molecular weight 209.25
Molecular formula C9H15N5O
Physical description White solid
Solubility DMSO (5 mg/ml), Ethanol (5 mg/ml)
Size 100 mg
Stability Stable for 2 years as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.