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MLS-532223

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GTPase inhibitor CAS#: none available Citations: 1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10

Product Code: ax42714 (5 mg)

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Product Specification

Function / pharmacology MLS-532223 is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.
Chemical name 1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
Molecular weight 251.24
Molecular formula C15H9NO3
Physical description Beige solid
Solubility DMSO (20 mg/ml)
Size 5 mg
Stability Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.