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N-Oleoylphenylalanine

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Mitochondria CAS#: NF Citations: 1) Long et al. (2016), The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria Cell, 166 424

Product Code: ax44540 (5 mg)

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Product Specification

Function / pharmacology An endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylalanine binds directly to mitochondria and functions as an endogenous uncoupler of UCP1-independent respiration and is the most potent in the group of structurally different lipoamino acids evaluated. Mice treated with an analog, C18-1-Leu, were found to have improved glucose homeostasis and increased energy expenditure.1
Chemical name N-Oleoyl Phe
Molecular weight 429.64
Molecular formula C27H43NO3
Physical description Off-white solid
Solubility DMSO (35 mg/ml)
Size 5 mg
Stability Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.