The immunogen for the anti-human p15 was a his-tagged recombinant full length p15 protein recognizing a 15kDa protein. The p15ink4b tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle.
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