Axol Human iPSC-Derived Cerebral Cortical Neurons express typical markers of cerebral cortical neurons, such as TBR1, CTIP2, TUJ1, BRN2 and CUX1. They are electrically active and able to form functional synapses and circuits in culture. This product is a plate of live cerebral cortical neurons in 96-well plate format. Axol Human iPSC-Derived Neural Stem Cells are seeded at the recommended plating density (70,000-200,000 cells/cm2) and synchronously differentiated to neurons for two weeks. For other conditions please inquire. Shipping restrictions apply to this product. Please inquire for availability in your region.
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Description
Human iPSC-Derived Cerebral Cortical Neurons (Female) - Plated
Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer’s disease, autism, epilepsy and frontotemporal dementia. Despite strong interest in these diseases, high quality human in vitro cell models for cortical neurophysiology have been unavailable until now. With our plated human iPSC-derived cerebral cortical neurons, we provide neuroscience researchers with assay-ready, pre-plated iPSC-derived neurons that have been highly characterised. Our in-house experts perform the plating and neuronal differentiation in order to save you time and increase the efficiency of your experiments.
This product is a 96-well plate containing pre-plated and pre-differentiated iPSC-derived cerebral cortical neurons. Neural Stem Cells are seeded at the recommended plating density (70,000-200,000 cells/cm2) on a 96-well plate coated with SureBond-XF and are synchronously differentiated to neurons for two weeks. For other conditions, please inquire. The plate is shipped fresh and therefore shipping restrictions apply to this product so please inquire to check availability in your region.
Product Specification
| Starting material | Cord blood CD34+ cells |
| Donor gender | Female |
| Donor age at sampling | Newborn |
| HLA serotype | A3 A33, B7(Bw6) B7(Bw6), Cw7 Cw7 |
| Karyotype | Normal |
| Reprogramming method | Episomal vector |
| Induction method | Monolayer & chemically defined medium |
| Genetic modification | None |
| Size | 1 x 96-well plate |
| Cell type | iPSC-derived cerebral cortical neurons |
| Growth properties | Adherent |
| Shipping conditions | Ambient |
| Usage notes | Upon receipt, incubate the plate at 37°C, 5% CO2 in a humidified incubator |
Technical Resources
References
- Read nowA. Odawara, H. Katoh, N. Matsuda, I. Suzuki. Induction of long-term potentiation and depression phenomena in human induced pluripotent stem cell-derived cortical neurons, Biochemical and Biophysical Research Communications (2015).
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