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Description
Axol’s Human iPSC-derived Microglia are generated using a fully defined medium from a factory of human iPSC-derived monocytes.
These highly validated Human iPSC-derived Microglia have been successfully used in multiple applications to evaluate functionality such as assessment for cytokine secretion by ELISA, phagocytosis capability by phagocytosis and efferocytosis assays, and changes in the production of reactive oxygen species (ROS) by ROS assays.
Human iPSC-derived Microglia reveals the expression of key microglia-specific markers, such as transmembrane protein 119 (TMEM119) and Purinergic Receptor P2Y12 (P2RY12), and the myeloid markers TREM2 and IBA-1.
Product Specification
Starting material
Cord blood CD34+ cells
Donor gender
Female
HLA serotype
A3 A33, B7(Bw6) B7(Bw6), Cw7 Cw7
Karyotype
Normal
Reprogramming method
Episomal vector
Size
1 x 96-well plate
Growth properties
Adherent
Shipping conditions
Ambient
Usage notes
Upon receipt, incubate the plate at 37°C, 5% CO2 in a humidified incubator
Axol’s Human iPSC-derived Microglia are generated using a fully defined medium from a factory of human iPSC-derived monocytes.
These highly validated Human iPSC-derived Microglia have been successfully used in multiple applications to evaluate functionality such as assessment for cytokine secretion by ELISA, phagocytosis capability by phagocytosis and efferocytosis assays, and changes in the production of reactive oxygen species (ROS) by ROS assays.
Human iPSC-derived Microglia reveals the expression of key microglia-specific markers, such as transmembrane protein 119 (TMEM119) and Purinergic Receptor P2Y12 (P2RY12), and the myeloid markers TREM2 and IBA-1.
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