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Primary Human Hepatocytes - Characterised

Axol's inventory includes hundreds of donor backgrounds to suit your individual research needs. Please enquire for latest donor availability and price.

Product Code: ax37501-1 Categories: .

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Description

Primary Human Characterised Hepatocytes  are isolated from whole human livers that are not suitable for liver transplantation. 

The cell composition consists of a homogenous population of hepatocytes which are characterized by viability, morphology, plating efficiency and various functional testing including multiple CYP450 basal and induction levels including CYP3A4, CYP2D6, CYP2C9, CYP1A2, and CYP2B6.  

Axol's Primary Human Characterised Hepatocytes will undergo an ECOD study for 7-HCG and 7-HCS formation, and finally each lot will be tested for its ability to maintain function for a minimum period of 5 days and will be reported on the quality control report delivered with each vial.

Please see our protocol/lot dependent for detailed instructions. Primary Human Hepatocytese protocols do change slightly depending on the lot. Some lots need to have an additional Percoll step. Culture vessels must be coated with Type I Collagen: ax3799 is recommend.

Use ax3754-1 Primary Hepatocyte Thaw Medium and ax3752-1 Primary Hepatocyte Maintenance Medium for cryosuspension (non plateable) lots. Use ax3751-1 Primary Hepatocyte Plating Medium for Plateable lots.

Full certificates of analysis are provided for each lot. Batch reservation is available on request.

All cells are tested and confirmed negative for HIV-1, HIV-2, HBV and HCV as detected by PCR. The cells are confirmed to be negative for mycoplasma and other detectable microbial contamination.

Axol's hepatocyte portfolio also includes 3D Hepatic Organoids and all of the research tools you need to complete your evaluation.


Product Specification

Donor gender Wide range of donor backgrounds available
Donor age at sampling Wide range of donor backgrounds available
Size >3 millions cells/vial *Lot dependent. Please inquire for latest lot quantity and price*
Shipping conditions Dry ice
Storage conditions vapour phase nitrogen
Usage notes Please see our protocol/lot dependent for detailed instructions. Culture vessels must be coated with Type I Collagen: ax3799 is recommend .