Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1) is a component of the hetero-pentameric receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. The receptor is a ligand-gated multi-subunit chloride channel. Mutations in the GABRA1 gene have been associated with juvenile myoclonic epilepsy and childhood absence epilepsy type 4.
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