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Purified anti-HSF2

Heat shock factor protein 2 (HSF2) is a transcription factor that enters the nucleus and binds to heat shock factor promoter elements, consisting of a consensus tandem array sequence of three oppositely oriented "AGAAN" motifs, during heat shock in eukaryotes.  Under normal conditions, it exists as a homodimer in the cytoplasm of cells where it binds to heat shock proteins and inactivates them.  During high temperature cellular stress, misfolding of proteins occurs, which causes heat shock proteins to dissociate from the heat shock factor proteins and bind to the misfolded proteins.  This leads to free heat shock proteins, which can then enter the nucleus and activate transcription. 

Product Code: ax33006414 (100 µl) Categories: .

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Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB
Host Rat
Specificity HSF2
Size 100 μl
Species reactivity Human, Mouse, Rat
Clonality Monoclonal
Clone number 3E2
Isotype Rat IgG1
Shipping conditions Ambient temperature
Storage conditions +4°C
Formulation Phosphate-buffered solution.