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Purified anti-PP2AC Methyl (Leu 309)

PP2AC (Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform), encoded by the PPP2CA gene, is the main phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2AC is reversibly methyl esterified on Leu-309 by leucine carboxyl methyltransferase 1 (LCMT1) and protein phosphatase methylesterase 1 (PPME1). This carboxyl methylation influences the affinity of the catalytic subunit for the different regulatory subunits, which in turn, modulates the PP2A holoenzyme's enzyme activity and cellular localization.

Product Code: ax33006392 (100 µl) Categories: .

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Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB
Host Mouse
Specificity PP2AC Methyl (Leu 309)
Size 100 μl
Species reactivity Human, Mouse, yeast
Clonality Monoclonal
Clone number 2A10
Isotype Mouse IgG1
Shipping conditions Ambient temperature
Storage conditions +4°C
Formulation Phosphate-buffered solution.