• Search

Purified anti-γ-protocadherin (pan reactive)

Purified anti-γ-protocadherin is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Product Code: ax33006469 (100 µl) Categories: .

Payment Options

We accept Visa and MasterCard in our online store.

Worldwide Shipping

We can get your purchases to you wherever you are.

Customer Care

As an Axol customer you have access to our support team and product specialists.

Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB
Host Mouse
Specificity g-protocadherin
Size 100 μl
Species reactivity Mouse
Clonality Monoclonal
Clone number N159/5
Isotype Mouse IgG1
Shipping conditions Ambient temperature
Storage conditions +4°C
Formulation Phosphate-buffered solution.