SAPAP is also known as DAP-1 or GKAP, encoded by the DLGAP1 gene. It is enriched in the postsynaptic membrane and is responsible for connecting PSD-95 and SHANK, which serves as an adapter protein that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton.
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