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Purified anti-Sortilin

Sortilin was originally purified from human brain tissue and was identified as a new lipoprotein receptor, which was later identified as a multifunctional sorting receptor of the VPS10P-domain receptor family. Although Sortilin is predominately expressed in neurons of the central and the peripheral nervous systems, it is also expressed in metabolic tissues including liver. Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is critical for lipid metabolism, and it has been implicated in lipid disorders. Sortilin is also an APOE receptor implicated in Alzheimer disease.

Product Code: ax33007294 (25 µg) Categories: .

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Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB, IHC-P
Host Rat
Specificity Sortilin
Size 25 µg
Species reactivity Human, Rat
Clonality Monoclonal
Clone number W16078A
Isotype Rat IgG2a, κ
Shipping conditions Ambient temperature
Storage conditions +4°C
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.