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Purified anti-TFEB

The autophagy-lysosomal pathway is involved in the degradation of long-lived proteins. The transcription factor EB (TFEB) plays a critical role in regulating basic cellular processes, such as lysosomal biogenesis and autophagy. The subcellular localization and activity of TFEB are regulated by mechanistic target of rapamycin (mTOR)-mediated phosphorylation. TFEB is also involved in physiological processes, and it induces the intracellular clearance of pathogenic factors in a variety of diseases, such as Parkinson's and Alzheimer's, suggesting that novel therapeutic strategies could be based on the modulation of TFEB activity.

Product Code: ax33007272 (25 µg) Categories: .

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Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB
Host Mouse
Specificity TFEB
Size 25 μg
Species reactivity Human, Mouse, Rat
Clonality Monoclonal
Clone number A17106C
Isotype Mouse IgG2a, λ
Shipping conditions Ambient temperature
Storage conditions +4°C
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.