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Purified anti-TFEB

The autophagy-lysosomal pathway is involved in the degradation of long-lived proteins. The transcription factor EB (TFEB) plays a critical role in regulating basic cellular processes, such as lysosomal biogenesis and autophagy. The subcellular localization and activity of TFEB are regulated by mechanistic target of rapamycin (mTOR)-mediated phosphorylation. TFEB is also involved in the clearence if intracellular pathogenic targets in a variety of diseases, such as Parkinson's and Alzheimer's, suggesting that novel therapeutic strategies could be based on the modulation of TFEB activity.

Product Code: ax33007272 (25 µg) Categories: .

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Features & Benefits

Higly Spesific Primary Antibodies

Product Specification

Application WB
Host Mouse
Specificity TFEB
Size 25 µg
Species reactivity Human, Mouse, Rat
Clonality Monoclonal
Clone number A17106A
Isotype Mouse IgG2a
Shipping conditions Ambient temperature
Storage conditions +4°C
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.