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Safracin B

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Anticancer agent CAS#: 87578-99-2 Citations: 1) Ikeda et al. (1983), Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo, 36 1279 2) Okumoto et al. (1985), Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo, 38 767

Product Code: ax132716 (1 mg)

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Product Specification

Function / pharmacology Novel antibiotics of the saframycin family produced by Pseudomonas fluorescens1. Safracin B displays antitumor activity agenst L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A2.
Molecular weight 540.61
Molecular formula C28H36N4O7
Physical description Yellow-green solid
Solubility DMSO (20 mg/ml)
Size 1 mg
Stability Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.