• Search

SHP-1

Recognizes a protein of ~50kDa, which is identified as the SH2-containing protein-tyrosine phosphatase 1 (SHP-1). This antibody is highly specific to SHP-1 and shows no cross-reaction with other protein-tyrosine phosphatase. SHP-1 is known to play a crucial role in the regulation of hematopoiesis and it regulates the transcriptional activity stimulated by the erythropoietin (EPO)-induced JAK/STAT and MAPK pathways and is involved in the signaling machinery responsible for erythroid differentiation and suppression of apoptosis. Furthermore, the observation that SHP-1 associates with RAFTK/Pyk2/CAK activated by beta-chemokine receptor (CCR5) and SHP-1 also associates with the adaptor protein Grb2 and the Src-related kinase Syk indicates the role of SHP-1 in modulating cell migration, proliferation, and immune functions.

Product Code: ax1085019 (100 µg) Categories: .

Payment Options

We accept Visa and MasterCard in our online store.

Worldwide Shipping

We can get your purchases to you wherever you are.

Customer Care

As an Axol customer you have access to our support team and product specialists.

Product Specification

Application Western Blot|Immunoprecipitation
Host Mouse
Size 100 µg
Species reactivity Human
Clone number 1SH01
Isotype IgG2b
Shipping conditions Ambient temperature
Storage conditions -20°C