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SMER3

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E3 UB ligase inhibitor CAS#: 67200-34-4 Citations: 1) Aghajanyy et al. (2010), Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor; Nat. Biotechnol., 28 738

Product Code: ax43132 (10 mg)

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Product Specification

Function / pharmacology Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor if the ubiquitin E3 ligase SCFMET30 both in vitro and in vivo.
Chemical name 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Molecular weight 224.18
Molecular formula C11H4N4O2S
Physical description Yellow solid (mp = 289-292°C)
Solubility DMSO (20 mg/ml)
Size 10 mg
Stability Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.