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TCF-4

TCF 4 (T cell factor 4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 4 generates transcriptionally active complexes with catenin in colon carcinoma cells. Expression of TCF 4 is highest in the CNS and intestinal epithelium where Wnt signaling also plays an essential role in development. Aberrant TCF 4 transcription activity has been implicated in carcinogenesis of intestinal and mammary epithlia.

Product Code: ax1085503 (100 µg) Categories: .

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Product Specification

Application Western Blot|Immunohistochemistry|Immunoprecipitation
Host Mouse
Size 100 µg
Species reactivity Human|Mouse
Clone number 6H5.3
Isotype IgG2a
Shipping conditions Ambient temperature
Storage conditions -20°C