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TW-37 is a potent inhibitor of BCL-2, which attenuates BCL-2 activation and inhibits multiple BCL-2 family members including BCL-XL and MCL-1. It binds to the BCL-2 homology domain 3 (BH3) groove of BCL-2, preventing the heterodimerization of proapoptotic proteins such as Bid, Bim, and Bad) with BCL-2 and subsequently allowing them to induce apoptosis. CAS No.: 877877-35-5 Molecular Formula: C33H35NO6S MW: 573.7 Purity: ≥95% Solubility: DMSO >100mM Storage Temp.: -20°C Handling: Protect from moisture

Product Code: ax1762784 (25 mg) Categories: .

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Product Specification

Function / pharmacology inhibitor of BCL-2
Chemical name TW-37
Molecular weight 573.7
Molecular formula C33H35NO6S
Physical description Solution
Solubility Soluble in water
Size 25mg
Shipping conditions Blue ice
Storage conditions -20°C
Stability -