• Search

Discovery Stems From Here

Find your tools for building human cell-based models & screening assays

Welcome to Axol Bioscience

YOUR HUMAN CELL CULTURE SPECIALISTS

Our mission is to create the best human cell biology research tools, to advance medical research and drug discovery

Latest News

  • Human iPSC-derived cardiomyocytes: studying cardiomyocytes in vitro

    Traditionally, there have been difficulties in obtaining and culturing human cardiac cells of a high quality due to a scarcity of healthy donor material, culture issues associated with the non-dividing state of terminally differentiated cardiomyocytes. The development of human embryonic stem cell technology allowed major advancements to be made as protocols were developed to differentiate cardiomyocytes from a replenishable pluripotent source. A huge issue with the use of human embryonic stem cell-derived cells was the controversial ethical issues and strict regulations regarding their use. This meant that Yamanaka's breakthrough when his group produced the Nobel Prize winning technology in the form of induced pluripotent stem cells had a gargantuan impact on the study of human cardiac cells.

  • A sit-down with Steve Rees: the importance of understanding renal toxicity in drug development

    Drug toxicity is a significant cause of clinical failure, accounting for approximately one third of all pipeline attrition. This has driven huge interest across the pharmaceutical industry to understand drug toxicity early within the drug development pipeline. The aim of this is to de-risk drug candidates from a safety perspective before they enter the clinic, as well as reducing the substantial costs associated with drug development.

  • Astrocytes: characteristics and function in development and disease

    Characterized by their star-like shape astrocytes, also known as astroglia, represent the most abundant cell type in the brain. Closely linked to neurons with pivotal roles in synaptic activity and blood-brain barrier function, the study of astrocytes using in vitro co-culture models is becoming increasingly important in neuroscience research.

  • Axol Bioscience launches human antibodies

    Our team has spent the first few months of 2018 working hard to introduce an exciting new range of products to the Axol catalog. As well as the Primary and iPS derived human cells Axol is know for; we can now offer researchers the convenience of sourcing antibodies, kits and other reagents in one place.

  • Reprogramming somatic cells to induced pluripotent stem cells (iPSC): A cellular career change

    Somatic cells can be compared to human beings in that they grow up to perform a specific function in life. While a human being may develop into a world class athlete or a research scientist, a somatic cell can develop into any of the cell types that make up an organism except the germline cells.