·       Extension of previous funding round brings total raised to £7 million GBP (circa $9.2 million USD)

    ·       Investment from Calculus Capital, Par Equity, and Scottish Enterprise

    ·       Funding will support continued development of Axol’s human iPS cell lines and reagents, and expansion of its commercial team


    Cambridge, UK, 7 April 2022: Axol Bioscience Ltd. (Axol), an established provider of iPSC-derived cells, media, and characterization services for life science discovery, today announced that it has raised £3.2 million GBP (circa $4.2 million USD) in the extension of its previous funding round, bringing the total raised to £7 million GBP (circa $9.2 million USD). The round was led by existing investors Calculus Capital, Par Equity and Scottish Enterprise, with support from Meltwind, including early investor Dr Jonathan Milner.


    The funds will be used to bring new human induced pluripotent stem cell (iPSC) products and service solutions for cardiac, neuroscience, and immune cell modeling to the drug discovery and screening markets, including Axol’s recently developed comprehensive in vitro proarrhythmia assay (CiPA)-validated human iPSC-derived cardiomyocytes. Funding will enable Axol to further optimize cell culture quality and iPSC manufacturing capabilities at its Edinburgh, UK, site based at the Roslin Institute, as well as support recruitment efforts to expand its commercial team. It will also facilitate the continued development of the Company’s digital platform.


    Liam Taylor, CEO, Axol Bioscience, commented: “At Axol, we’re setting a new standard in iPSC quality and manufacture. This investment enables us to continue to build and apply our quality-driven mindset to develop robust, reliable, ready-to-use iPSCs for pre-clinical R&D and drug development, as well as to focus on the expansion of our commercial team.”


    Dr Thomas Stratford, Interim Chairman, Axol Bioscience, added: “We are delighted to have secured additional funding from our existing investors in this oversubscribed round. This reflects both the potential of Axol’s iPSC technology and products, and the unrivalled expertise of our team. This investment reinforces our ongoing mission to develop the high-quality, validated human cell biology tools needed to drive innovation in medical research and drug discovery.


    Dr Jonathan Milner, Investor and CEO, Meltwind, said: “Axol is well positioned in the global iPSC market to support advances in drug screening and discovery. We look forward to the Company’s future iPSC product developments, poised to provide more physiologically relevant and consistent human disease models and screening assays to, ultimately, progress next-generation therapies for neuroscience and cardiac diseases to the clinic, faster.”


    About Axol Bioscience www.axolbio.com

    Axol Bioscience Ltd has been an industry leader for nearly a decade in the supply of human iPSC-derived cells from healthy and disease-state donors. Those products are supported and enhanced by optimized cell culture systems and media formulations that ensure quality, consistent cell behaviors, and expedited maturation. In addition, Axol is an experienced provider of custom services for disease modeling and toxicity screening to support drug discovery.


    To best serve a growing drug discovery customer base, Axol continues to add in-demand assay capabilities to better characterize product cell lines and provide custom services. Most recently, Axol added electrophysiology capability and expertise with an in-house multi-electrode array system and a dedicated scientific thought leader in the area to guide customers and collaborators through relevant data sets for the best disease or functional cell models for their applications.


    Follow Axol Bioscience on Twitter @axolbio and LinkedIn @Axol Bioscience Ltd


    About Calculus Capital www.calculuscapital.com

    Calculus is a multi-award winning VCT and EIS fund manager. It received two Outstanding Contribution awards at the EIS Association 25th Anniversary Awards in 2019. It was voted Best EIS Investment Manager at the 2018 Growth Investor Awards. It has been named Best EIS Fund Manager five times at the EIS Association Awards and won Best Generalist EIS 2017/18 at the Investment Week Tax Efficiency Awards. It launched the UK’s first approved EIS fund in 1999 and has 20-year track record of investing in genuine UK growth companies.


    Calculus has unparalleled experience of working with smaller UK companies to support their growth, development, scale-up and exit. It manages the multi-sector Calculus EIS Fund and Calculus VCT, as well as the UK Content Creation EIS Fund, which was launched in association with the BFI to deliver vital equity funding to the UK’s most promising content creation companies.


    Calculus Capital is authorised and regulated by the Financial Conduct Authority


    About Meltwind Advisory LLP www.meltwind.co.uk

    Meltwind Advisory LLP are the due diligence and portfolio management team for Jonathan Milner, founder and former CEO of Abcam. Jonathan invests as an Angel across the life sciences, supporting early-stage companies throughout their journey with investment and guidance.


    About Par Equity www.parequity.com

    Par Equity is a leading venture capital firm, based in Edinburgh, investing across the North of the UK in innovative technology companies, with high growth potential. Since it was founded in 2008, Par Equity has now invested more than £123m across 71 companies, leveraging a further £209m of capital from third party investors.  


    Par’s investment thesis is to combine the professionalism and rigour of a venture capital manager with the skills and expertise of a broad base of individual investors who can add value throughout the investment life cycle. This investment approach has produced exceptional outcomes across 23 realisations to date, with Par winning the Best EIS Investment Manager at the 2021 EISA (Enterprise Investment Scheme Association) Awards and Best Angel Group at the UK Business Angel Association Awards 2021.


    About Scottish Enterprise www.scottish-enterprise.com

    Scottish Enterprise is Scotland's national economic development agency and a non-departmental public body of the Scottish Government. To deliver a significant, lasting effect on the Scottish economy, we work with partners in the public and private sectors to find and exploit the best opportunities.

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    Axol Bioscience is a Key Participant in the European Union's Horizon 2020 Research Programme